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Many stem cell transplants have been curative with a 90% survival but only 18% of eligible patients have an acceptable match.

The multicenter trials of hydroxyurea in the 1980s and 90s as preventive therapy reduced the need for blood transfusions, pain events and hospitalizations. This was approved for medical use by the FDA in 1998.

Education on SCD was given to students in almost all Health Training Institutions and Senior High Schools in the three regions.

Informal Education: The approach used was community based health education.

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Gene therapy that delivered an antisickling variant of hemoglobin in an autologous hematopoietic stem cell (HSC) transplant had ameliorated all the symptoms of severe sickle cell disease (SCD) in a 15-year-old boy 2 years out from the procedure. The Sickle Cell Condition Advocates (SICCA), a registered Non-Governmental Organization (NGO) which has been in operation since September 2007 is involved in many activities which aims at educating, counseling, raising awareness on SCD and reducing it to the barest minimum in the long term.

This may reflect a lack of access to high-quality comprehensive care for adults with SCD in the US. Gifty Tina Naa Ayeley Mensah Corresponding Author: Email: [email protected]

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